Abstracts (Poster presentations)

Poster presentations at National and International medical conferences

  1. Thiopurine withdrawal during sustained clinical remission in inflammatory bowel disease: relapse and recapture rates in 72 patients, a report from a district general hospital.

P Radhakrishnan, HE Johnson, KP Wade, SD McLaughlin JCC 2019

  1. New guidance on therapeutic drug monitoring; potential clinical and cost implications

R. Felwick, H. Johnson, H. Dewhurst, E. Cadogan, C. Hovell, S. Weaver, S. McLaughlin

JCC 2018

  1. Efficacy and safety of Azathioprine and methotrexate for maintaining remission in microscopic colitis; outcomes from a District General Hospital.

H.E Johnson, S.D McLaughlin  Falk 2018

  1. Long term outcomes of initial infliximab therapy for inflammatory pouch pathology: a multi-centre retrospective study

J Segal, LPenez, S Elkady, G Worley, S McLaughlin, B Mullish, M Quraishi, N Ding, T Glyn, K Kandiah, M Samaan, P Irving, O Faiz, S Clark, AHart

Gut 2018

  1. The Follow up of coeliac serology at a large district general hospital; results in 14029 patients

GC. Read, SR. Whiteoak, A Grainey, SD McLaughlin

Gut 2017

  1. The introduction of infliximab therapeutic drug level monitoring is associated with

cost savings in a cohort of patients in a large district general hospital

S Whiteoak, H Johnson, C Hovell, S Weaver, S McLaughlin

JCC 2017

  1. Does switching to low dose thiopurine and allopurinol prevent IBD patients with evidence of

hypermethylation on standard dose thiopurines from developing hepatotoxicity and drug side effects

Wade KP, Johnson HE, Slinger K, Hovell CJ, Weaver SA, McLaughlin SD

JCC 2017

  1. Outcome of 114 patients admitted with acute severe ulcerative colitis over 5 years

at a district general hospital

K Wade, H E Johnson, S A Weaver, S D McLaughlin

JCC 2017

  1. Is febuxostat the solution for patients who develop side effects to low dose azathioprine and

allopurinol co-therapy?

Johnson HE, Wade KP, Hovell CJ, Weaver SA, McLaughlin SD

JCC 2017

  1. Introduction of An Inflammatory Bowel Disease Nurse Flexible Sigmoidoscopy Clinic Improves Patient Care by Initiating Earlier Treatment and Saves Clinic Slots

HE Johnson, SA Weaver, SD McLaughlin

Gut 2016;65:Suppl 1 A37-A38 K Wade, H Johnson, H Dewhurst, S Weaver, S McLaughlin

  1. T Raine, A Bassi, E Fogden, B Hayee, J K. Limdi, H Ludlow, S McLaughlin, G C Parkes, P Patel, M Smith, CP Selinger

Excess steroid use in IBD: too much, how much and why? Results from a UK nationwide audit

Gastroenterology 2016

  1. Low uptake of cervical screening in immunosuppressed patients with inflammatory bowel disease at a district general hospital 
K Gut 2015;64:Suppl 1 A234
  2. HE Johnson, K Wade, S Weaver, S McLaughlin

Screening for enteric infection in inflammatory bowel disease patients contacting the ibd helpline and presenting with disease flares

Gut 2015;64:Suppl 1 A230

  1. H Robertson, S Harding, S McLaughlin

Endoscopic removal of buried bumper PEGs. Outcome of a novel technique from a district general hospital

Gut 2015;64:Suppl 1 A518 doi:10.1136/gutjnl-2015-309861.1133

  1. Dietitian-led virtual coeliac disease clinic results in in cost savings and and increased patient satisfaction

Stuckey C, Martin H, McLaughlin SD

Gut. 2014 Jun;63 Suppl 1:A219

  1. Low dose azathioprine and allopurinol in azathioprine intolerant patients: is it tolerated and is it effective in IBD?

H Johnson, S Weaver, S McLaughlin

Gut 2014 Suppl 1, A29

  1. Diagnostic benefit of MRE following CT

Dharmasiri S, Boud R,  Dower A, Hennesey N, Standing L, Richard-Taylor A,  Johnson HE, Weaver SA, McLaughlin SD

Gastroenterology 2014

  1. Azathioprine in the elderly – Is it tolerated and is it safe?

Dharmasiri, S., Johnson, H.E., McLaughlin, S.D., Weaver, S.A.

JCC 2014

  1. Low dose azathioprine and allopurinol co-therapy: is it safe to use without metabolite monitoring?

B M Eross, H E Johnson, S A Weaver, S D McLaughlin

JCC 2014

  1. H Dewhurst, H.E. Johnson, S.A. Weaver, S.D. McLaughlin

Low-dose thiopurine and allopurinol co-therapy results in significant cost savings at a district general hospital

JCC 2013

  1. Dewhurst H, Johnson HE, Begley JP, Weaver SA, McLaughlin SD The routine measurement of thiopurine metabolite levels results in dose optimisation in the majority of IBD patients; results from a district general hospital.

JCC 2013

  1. K Smith, H.E. Johnson, N. Jarrett, S.D. McLaughlin, S.A. Weaver Long Term Outcome of Azathioprine therapy in 353 Consecutive IBD Patients at a district general hospital

JCC 2013

  1. R Basuroy, H E Johnson, T Hollingworth, S A Weaver, S D McLaughlin Efficacy of Methotrexate in Ulcerative Colitis: A District General Hospital Experience

Gut 2013;62:Suppl 1 A249 doi:10.1136/gutjnl-2013-304907.580

R Willington, V Lashmar, K Benes, K Barnett, S Weaver, R McCrudden, T Smith, C Gordon, P Cilclitira, S McLaughlin

  1. Coeliac Serology and Negative Duodenal Biopsy

Gut 2013;62:Suppl 1 A286 doi:10.1136/gutjnl-2013-304907.671

T Hollingworth, H Johnson, R Basuroy, S Mclaughlin, S Weaver

Outcome of Ulcerative Colitis Patients that have Failed Conventional Thiopurine Therapy; Allopurinol Co-Therapy and Beyond

Gut 2013;62:Suppl 1 A257-A258 doi:10.1136/gutjnl-2013-304907.602

  1. R Willington, V Lashmar, K Benes, K Barnett, S Weaver, R McCrudden, T Smith, C Gordon, P Cilclitira, S McLaughlin

Push Enteroscopy Leads to a Change in Diagnosis in the Majority of Patients with Positive

Coeliac Serology and Negative Duodenal Biopsy

Gut 2013;62:Suppl 1 A286 doi:10.1136/gutjnl-2013-304907.671

  1. J Landy, H O Al-Hassi, E R Mann, S T Peake, S D McLaughlin, Z L Perry-Woodford, P J Ciclitira, J Nicholls, S K Clark, S C Knight, A L Hart

A Prospective Controlled Pilot Study of Fecal Microbiota Transplantation for Chronic Refractory Pouchitis

Gut 2013;62:Suppl 1 A162 doi:10.1136/gutjnl-2013-304907.367

  1. B M Shandro, R Basuroy, L Gamble, S Edwards, S Al-Shamma, S D McLaughlin First Year Results from a Virtual Iron Deficiency Anaemia Service at a District General Hospital

Gut 2013;62:Suppl 1 A264-A265 doi:10.1136/gutjnl-2013-304907.618

  1. B Patel, S McLaughlin, E Williams, S Al-Shamma

Metabolic Bone Disease in Mild Chronic Liver Disease- is it Worth Checking?

Gut 2013;62:Suppl 1 A84-A85 doi:10.1136/gutjnl-2013-304907.186

  1. K Thavanesan, K Barnett, S Harding, D Hartley, S Al-Shamma, S A Weaver, S D McLaughlin Mortality After Peg: Review of 259 Peg Procedures at a District General Hospital over A 7 Year Period

Gut 2013;62:Suppl 1 A204-A205 doi:10.1136/gutjnl-2013-304907.470

  1. H M Dewhurst, H E Johnson, J Begley, S A Weaver, S D McLaughlin The Routine Measurement of Thiopurine Metabolite Levels Results in Dose Optimisation in One Third of IBD Patients; Results from a District General Hospital

Gut 2013;62:Suppl 1 A253 doi:10.1136/gutjnl-2013-304907.591

  1. J Landy, H O Al-Hassi, E R Mann, S T Peake, S D McLaughlin, Z L Perry-Woodford, P J Ciclitira, J Nicholls, S K Clark, S C Knight, A L Hart

The Effects of Faecal Microbiota Transplantation on the Innate Immune System and Epithelial Tight Junction Expression in Chronic Refractory Pouchitis

Gut 2013;62:Suppl 1 A40-A41 doi:10.1136/gutjnl-2013-304907.092

  1. Kodjabashia K, Hayder SA, Lashmar VL, Crossland C, McLaughlin SD

Celiac serology at a large district general hospital, results in 6394 patients

Gastroenterology 2012

  1. Johnson HE, Weaver SA, McLaughlin SD,

Azathioprine and allopurinol co-therapy for IBD patients is a safe and effective treatment option in the district general hospital setting

JCC 2012

  1. Sahebjalal M, Blackman J, McLaughlin S

The Reintroduction of Antiplatelet Agents Post Gastrointestinal Haemorrhage: A retrospective cross-sectional study and proposed management algorithm

  1. Clin Gastroenterol Hepatol 2012

Johnson HE, McLaughlin SD, Weaver SA

Azathioprine maintenance therapy in IBD: medium term outcomes from a nurse-delivered IBD monitoring service at a district general hospital

Gut Vol. 60 (Supp. 1) 2011

  1. Dolman GE, Johnson HE, McLaughlin SD, Begley JP, Weaver SA

6-Thioguanine measurement allows optimization in management of IBD patients on azathioprine

Gut Vol. 60 (Supp. 1) 2011

  1. McLaughlin SD, Borrow D, Anderson SHC

Single balloon enteroscopy; initial experience from a UK tertiary centre

Gut Vol. (Supp1.) 2010

  1. McLaughlin SD, Clark SK,  Shafi S, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2009

Maintenance antibiotic therapy in chronic pouchitis: experience in UK clinical practice

Gastroenterology Vol.136, Issue 5, (Supp. 1)

  1. McLaughlin SD, Culkin A, Clark SK,  Tekkis PP, Ciclitira PJ, Whelan K, Nicholls RJ. 2009

Treatment with elemental diet improves symptoms of chronic pouchitis following Ileal pouch-anal anastomosis for ulcerative colitis

Gastroenterology Vol.136, Issue 5, (Supp. 1)

  1. McLaughlin SD, Clark SK,  Tekkis PP, Ciclitira PJ, Nicholls RJ. 2009

Clostridium difficile and extended spectrum beta-lactamase resistant bacteria in UK chronic pouchitis patients

Gastroenterology Vol., Issue 5, (Supp. 1)

  1. McLaughlin SD, Clark SK,  Perry-Woodford ZL, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2009

Medina catheter use following Ileal pouch-anal anastomosis: Quality of life and functional outcome

Gastroenterology Vol. 136, Issue 5, (Supp. 1)

  1. McLaughlin SD, Clark SK, ZL Perry-Woodford, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2009

Quality of life and functional outcome in patients using a medina catheter following restorative proctocolectomy

Gut Vol. 58 (Supp. 1) A93

  1. McLaughlin SD, Clark SK, Shafi S, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2009

Maintenance antibiotic therapy for chronic pouchitis, complications and clinical outcome

Gut Vol. 58 (Supp. 1) A93

  1. McLaughlin SD, Clark SK, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2009

Clostridium difficile and extended spectrum beta-lactamase resistant bacteria in pouchitis patients

JCC Vol. 3, Iss. 1, P321

  1. McLaughlin SD, Clark SK, ZL Perry-Woodford, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2009

Medina catheter use following restorative proctocolectomy for ulcerative colitis: Quality of life and functional outcome

JCC Vol. 3, Iss. 1, P065

  1. McLaughlin SD, Haycock AV, Moran CP, Clark SK, Tekkis PP, Ciclitira PJ, Nicholls RJ1, Knowledge of the investigation and management of patients who have undergone pouch surgery is lacking in gastroenterology trainees.

JCC Vol. 3, Iss. 1, P065

  1. McLaughlin SD,  Clark SK, Wall R,  Maeda Y, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2008

Stool coliform testing can predict effective treatment regimes for patients with antibiotic resistant pouchitis

Colorectal Disease, Vol. 10, (Supp. II)  F012.

  1. McLaughlin SD, Culkin A, Petrovska L, Clark SK, Tekkis PP, Ciclitira PJ, Whelan K, Nicholls RJ 2008

Elemental diet improves symptoms in chronic pouchitis: preliminary report of an ongoing study

Colorectal Disease, Vol. 10, (Supp. II)  P47.

  1. McLaughlin SD, Haycock A, Clark SK, Tekkis PP, Nicholls RJ, Ciclitira PJ. 2008

Knowledge of the investigation and management of patients who have undergone pouch surgery is lacking in gastroenterology trainees.

Colorectal Disease, Vol. 10, (Supp. II)  P96.

  1. Maeda Y, Molina ME, Norton C, McLaughlin SD, Vaizey CJ, Laurberg S, Clark SK. 2008

The role of pouch compliance in management of pouch dysfunction

Colorectal Disease, Vol. 10, (Supp. II)  FO14

  1. Von Roon AC, Abecia L, Maronecles M, Boown DT, McLaughlin S, Paraskeva, Nicholls RJ, Tuohy KM, Tekkis PP. 2008

Pouchitis is associated with decreased faecal lactobacillus/enterococci populations

Colorectal Disease, Vol. 10, (Supp. I), P137.

  1. McLaughlin SD, Bell AJ, Clark SK, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2008

Antibiotics are effective for the treatment of pre-pouch ileitis following restorative proctocolectomy. Colorectal Disease, Vol. 10, (Supp. I)

  1. McLaughlin SD, L Petrovska, Walker A, Clark SK, Johnson MW, Tekkis PP, Parkhill J, Dougan G, Ciclitira PJ, Nicholls RJ. 2008

Dysbiosis and pouchitis, evidence from 16srRNA sequencing.

Gastroenterology Vol. 134, Issue 4 (Supp. 1)

  1. McLaughlin SD, Bell AJ, Postgate AJ, Clark SK, Tekkis PP, Ciclitira PJ,

Nicholls RJ. 2008

Missed Crohn’s disease is unlikely as a cause of unexplained iron deficiency in pouch patients: evidence from video capsule endoscopy.

Gastroenterology Vol. 134, Issue 4 (Supp. 1)

  1. McLaughlin SD, Perry-Woodford AZ, Johnson MW, Clark SK, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2008

High incidence of osteoporosis in patients over 50 following restorative proctocolectomy with IPAA suggests need for routine DXA screening

Gastroenterology Vol. 134, Issue 4 (Supp. 1)

  1. McLaughlin SD, Clark SK, Bell AJ, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2008

Incidence and implications of pre-pouch ileitis following restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis

Gastroenterology Vol. 134, Issue 4 (Supp. 1)

  1. McLaughlin SD, Bell AJ, Clark SK, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2008

Combined ciprofloxacin and metronidazole is highly effective for the treatment of pre-pouch ileitis following restorative proctocolectomy

Gastroenterology Vol. 134, Issue 4 (Supp. 1)

  1. McLaughlin SD, Johnson MW, Clark SK, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2008

VSL#3 for chronic pouchitis; experience in UK clinical practice

Gastroenterology Vol. 134, Issue 4 (Supp. 1)

  1. McLaughlin SD, Johnson MW, Clark SK, Tekkis PP,Ciclitira PJ, Nicholls RJ. 2008

Clinical experience with VSL#3 in patients with chronic pouchitis.

Gut 57 (Suppl. I) A136.

  1. McLaughlin SD, Clark SK, Bell AJ, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2008

Incidence and Implications of pre-pouch ileitis in patient following restorative proctocolectomy. Gut 57 (Suppl. I) A27.

  1. McLaughlin SD, Perry-Woodford AZ, Johnson MW, Clark SK, Tekkis PP, Ciclitira PJ, Nicholls RJ, 2008

Osteoporosis in patients over 50 following restorative proctocolectomy for ulcerative colitis, is DEXA screening warranted? Gut 57 (Suppl. I) A89.

  1. McLaughlin SD, Bell AJ, Clark SK, Tekkis PP, Ciclitira PJ, Nicholls RJ. 2008.

Missed Crohn’s disease is unlikely as a cause of unexplained iron deficiency in pouch patients: evidence from video capsule endoscopy. Gut 57 (Suppl. I) A137

  1. Johnson MW, Rogers GB, McLaughlin SD, Bruce KD, Forbes A, Ciclitira PJ, Nicholls RJ, 2007

The characterization of bacterial community diversity in cultures derived from healthy and inflamed ileal pouches after restorative proctocolectomy, using 16s ribosomal DNA terminal restriction fragment length polymorphism profiling.

Gut 56 (Suppl II) A5.

  1. Das P, Colucci G, McLaughlin SD, Clark SK, Guenther T, Nicholls RJ. 2007

Does indefinite diversion (ID) of the ileal pouch prevent further pouchitits?

Colorectal disease 9 (Suppl. 3), 2-7, F12.

  1. McLaughlin SD, Dewar DH, Johnson MW, Ellis HJ, Ciclitira PJ 2007

Investigation and management of patients referred with non-responsive coeliac disease: results of 110 cases.

Gut 56 (Suppl II) A57.

  1. McLaughlin SD, Harris AW 2007

Audit of 30 day mortality following PEG insertion at a district general hospital, The Kent and Sussex hospital, Tunbridge Wells, Kent: compared with NCEPOD results.

Gut 56 (Suppl II) A95.

  1. Ellis HJ, McLaughlin SD, Dewar D, Suligoj T, O’Sullivan C, Ciclitira P 2007

Monoclonal antibodies to the coeliac immunodinant gliadin peptide

Gut 56 (suppl II), A43.

  1. Ellis HJ, McLaughlin SD, Dewar D H, Gonzalea-Cinca N, Van Der Meer I, Van Den Broeck H, Weiser H, O’Sullivan C, Ciclitra P. 2007

Monoclonal antibodies raised against high molecular weight glutenins Gut 56 (Suppl. II) A143.

  1. McLaughlin SD, Harris AW 2005

The effect of Kent and Medway dyspepsia guidelines on the demand for open access endoscopy.Gut 56 (Suppl. II), A109.

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